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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
14.55
Human Site:
Y670
Identified Species:
29.09
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
Y670
L
V
C
Q
E
L
G
Y
S
Y
V
E
L
N
A
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
Y670
L
V
C
Q
E
L
G
Y
S
Y
V
E
L
N
A
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
Y670
L
V
C
Q
E
L
G
Y
S
Y
V
E
L
N
A
Dog
Lupus familis
XP_536259
1145
128125
Y667
L
V
C
Q
E
L
G
Y
S
Y
V
E
L
N
A
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
K667
N
A
S
D
T
R
S
K
N
S
L
K
A
V
V
Rat
Rattus norvegicus
NP_445999
1131
125770
K665
N
A
S
D
T
R
S
K
N
S
L
K
A
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
V753
E
E
L
G
Y
S
F
V
E
L
N
A
S
D
T
Chicken
Gallus gallus
NP_001006456
1147
128454
S667
V
C
K
E
L
G
Y
S
Y
V
E
L
N
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
R566
G
M
A
G
N
E
D
R
G
G
M
Q
E
L
I
Honey Bee
Apis mellifera
XP_397246
911
103001
G491
L
L
M
D
E
V
D
G
M
A
G
N
E
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
E486
E
D
R
G
G
I
Q
E
L
I
Q
M
I
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
A441
R
G
G
V
G
Q
L
A
Q
F
C
R
K
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
0
0
N.A.
N.A.
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
6.6
20
N.A.
N.A.
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
0
0
9
0
9
0
9
17
9
34
% A
% Cys:
0
9
34
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
25
0
0
17
0
0
0
0
0
0
17
0
% D
% Glu:
17
9
0
9
42
9
0
9
9
0
9
34
17
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% F
% Gly:
9
9
9
25
17
9
34
9
9
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
0
9
9
9
% I
% Lys:
0
0
9
0
0
0
0
17
0
0
0
17
9
9
0
% K
% Leu:
42
9
9
0
9
34
9
0
9
9
17
9
34
9
0
% L
% Met:
0
9
9
0
0
0
0
0
9
0
9
9
0
0
0
% M
% Asn:
17
0
0
0
9
0
0
0
17
0
9
9
9
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
34
0
9
9
0
9
0
9
9
0
0
0
% Q
% Arg:
9
0
9
0
0
17
0
9
0
0
0
9
0
0
9
% R
% Ser:
0
0
17
0
0
9
17
9
34
17
0
0
9
0
17
% S
% Thr:
0
0
0
0
17
0
0
0
0
0
0
0
0
9
17
% T
% Val:
9
34
0
9
0
9
0
9
0
9
34
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
34
9
34
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _